Study Finds Long-term Nicotine Use Causes No Harm

Nicotine in E-liquid causes no harm

We are all aware of the health risks associated with smoking cigarettes, and most people assume that nicotine plays a part in those risks. While nicotine is what gives smoking that pleasurable experience, it is not responsible for causing lung disease, cancer, or other smoking related illnesses.


Back in 1996 a paper was published in the scientific journal Life Science, detailing research on long-term nicotine exposure in rats. The rats were kept in a chamber with airborne nicotine that gave them twice the blood plasma nicotine concentration of the average smoker. They were in the chamber 20 hours per day, five days a week, for a period of two years. As a result they were exposed to nicotine at a much higher concentration than the majority of smokers are.

The results may surprise you. The rats who were in these nicotine-induced chambers did not have a higher mortality rate than other rats who were housed in normal cages. There was no increase in the rates of atherosclerosis, heart problems, or any kind of cancer, including lung cancer. There was also no increase in common precursor cells to lung cancer called pulmonary neuroendocrine cells, indicating that the nicotine did not increase the rats’ risk of developing lung cancer.

Rats in nicotine-filled cages showed no increase in diseases

There was one statistically significant difference between the two groups of rats. The ones in the nicotine-filled chambers had a lower body weight compared to those not given nicotine. However, this difference did not obviously affect their health or well-being.

This is great news for us Vapers!


It is very important to get the highest quality e-liquid available – you should know what’s going in your body. Visit one of Pink Spot’s two Las Vegas store locations or call us at 702-655-8273 for more information about our top-of-the-line products!

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Written by Pink Spot Vapors

Pink Spot Vapors

We created PSV in 2009 after being disappointed constantly with the quality of liquid and customer service in this industry. Our mission is to create the best quality and most unique eJuice flavors in the world. We only use Pharma grade nicotine, U.S. food grade 100% kosher PG/VG and food grade flavorings.

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